Essay On Scaffolds - 819 Words

Currently, there is a global increase in cases of bone disorders and conditions, which is expected to increase as twice as much by 2020 particularly in countries where obesity and poor physical activity are associated with aging[1]. Although reconstructive orthopaedic surgery can be used to treat bone defects and injuries caused by trauma, additional treatments are required for severe breaks or pathological conditions as well as critical bone defects due to malformation, cancer or osteoporosis in order to effectively stimulate healing and regeneration. While traditional autologous and allogeneic bone grafting is ineffective for treating large injuries because of lack of graft vascularization, low cell viability in the host, and other†¦show more content†¦Poly (ÃŽ µ-caprolactone) is an aliphatic polyester that is commonly used for biomedical applications as well as for tissue engineering and drug delivery. The physical and biological properties of PCL makes it a useful biomed ical material[7]. Because PCL contains five CH2 Moieties in its repeating units, it doesnt degrade quickly which makes it suitable for commercial sutures or delivery devices as well as for applications requiring a long term load[8]. In addition, due to the fact that the aliphatic ester linkage of PCL is susceptible to hydrolysis, it is likely to undergo hydrolytic degradation [4, 5, 9]. Poly(lactic-co-glycolic acid) (PLGA) is a good material for preparing scaffolds because its material properties can be modified to be more extensive by adjusting the molecular range as well as the lactic acid (LA)/glycolic acid (GA) ratios, unlike the poor characteristics exhibited by pure polylactic acid and polyglycolic acid. PLGA has been extensively used in bone tissue engineering in various ways (7-10). It is widely believed that the mechanical properties of bone tissue can be supported by PLGA scaffolds which take about 4 to 8 weeks to construct [10-12]. The orange/yellow pigment that is responsibleShow MoreRelatedEssay On Scaffolds902 Words   |  4 Pagesinvolving tissue engineering, biological and synthetic laryngeal scaffolds have been of much interest in recent times (Lott 2014). Although laryngeal allotransplantations are able to relatively quickly restore some degree of function not obtainable via artificial systems, for now, they do not present as a viable outcome for restoring function until issues associated with immunogenicity are solved. Emerging solutions – biological larynx scaffolds Following recent developments in biomaterials research, theRead MoreEssay On Scaffolds972 Words   |  4 PagesDevelop 3D printable natural and synthetic polymer systems, for biological scaffolds, that are tough enough to produce highly complex parts with small internal features and porosity to allow for microvascular regrowth to attach onto the scaffolds. To obtain a scaffold with suitable mechanical and viscoelastic properties (Young’s modulus 0.35 ± .11 MPa, Tensile stiffness 8.59 ±3.5 MPa, Equil. Modulus 13.6 ±1.5 MPa), it is very important to choose the proper polymeric material and fabrication technique10Read MoreScaffold Plank Essay1758 Words   |  8 PagesDianne Estrada Management Strategy Kucinski September 9, 2010 THE SCAFFOLD PLANK INCIDENT OVERVIEW Bob Hopkins, a previous banker, accepted a â€Å"trader† position with White Lumber, who was one of the bank’s best accounts. John White, the owner of White Lumber, was a director at the bank Bob previously worked for and a leading citizen in the community. The â€Å"trader† position Bob accepted involved buying and selling lumber. Bob’s compensation was incentive-based without a salary cap. The ethicalRead More The Scaffold of Sin in The Scarlet Letter Essay1144 Words   |  5 PagesThe Scaffold of Sin in The Scarlet Letter   Ã‚  Ã‚   This scaffold constituted a portion of a penal machine . . . . The very ideal of ignominy was embodied and made manifest in this contrivance of wood and iron (Hawthorne 62-63). A scaffolds effect on the novel can be seen through an examination of the first, second, and third scaffold scenes.   These sections mark the beginning, middle, and end of the novel. The novel The Scarlet Letter, by Nathaniel Hawthorne, is constructedRead More Scarlet Letter Scaffold Scenes Essay655 Words   |  3 PagesNathaniel Hawthorneamp;#8217;s, The Scarlet Letter, the author uses three scaffold scenes to mark the development of Hester Prynne. The image of Hester atop the scaffolding is a metaphor for her forced solitude; for her banishment from society; and for the futility of her punishment. In the first scene, Hawthorne uses the scaffold to explain how Hester can not believe that the amp;#8220;A; and the baby are real. In the second scaffold scene, Hawthorne tries to convey to the reader that Hester has fullyRead MoreEssay on Symbolism of the Scaffold in The Scarlet Letter939 Words   |  4 Pagesmost important symbol among them is certainly the scaffold in the market place, where the story begins and ends. The scaffold’s meaning changes throughout the story and has different values for different characters. It represents humiliation, then insi ght, and finally redemption for Hester and Dimmesdale, but for Chillingworth, it symbolizes birth of sin, growth of sin, and ultimately consummation by sin. At the beginning of the story, the scaffold â€Å"constituted a portion of a penal machine† (48)Read MoreScaffold Scenes In The Scarlet Letter Essay892 Words   |  4 PagesNathaniel Hawthornes The Scarlet Letter, the author uses three scaffold scenes to represent the change in Hester Prynne. The image of Hester atop the scaffolding is a metaphor for her banishment from society, and for the pointlessness of her punishment. The three scaffold scenes have a numerous amount of similarities, but they also have quite a few differences. In the first scaffold scene, Hester Prynne and her child Pearl stand on the scaffold. Hester has just been released from prison, and she is sentRead More Character evolution through three scaffold scenes Essay961 Words   |  4 Pagessymbol is the scaffold. During this period in time, the scaffold was used for public humiliation. Those who had committed either a crime or a sin were forced to stand upon it in front of everybody in the town, as a form of confession or public recognition of one’s sin. In The Scarlet Letter, the scaffold not only represents the act of confessing but it also can be seen as a symbol of the stern, inflexible doctrine of the Puritan faith. The Scarlet Letter is centered on the three scaffold scenes, whichRead MoreEnders Game and the Matrix - Comparative Essay Practise Essay Scaffold - Science Fiction1597 Words   |  7 Pagesâ€Å"In a comparative study of texts we see that the connections between texts are realised through the different textual f orms used by each composer.† How accurate is this statement for the pair of texts you have studied in this unit? In your answer you may like to discuss some or all of the following: form, structure, language features, context, information ideas. When texts are considered together, responders realise that texts are connected through their similar themes and ideas displayed inRead MoreHow Does the Scarlet Letter Comment on Religion in America? Essay754 Words   |  4 Pagestranscendental movement is also reflected in the novel. This essay argues that â€Å"The Scarlet Letter† condemns the Puritan society for its rigid and oppressive rules and generally it comments on the religion in America through portrayal of characters, setting and themes. Therefore this essay will describe how the characters, setting and themes in the Scarlet letter comment on the religion in America by exploring the scene of puritan morality, scaffold and through the interpretation of the Scarlet Letter â€Å"A†